The Effect of Corncob (Zea mays) Extract Cream on the Number of Melanin Pigments of Guinea Pig Exposed to Ultraviolet

Background: Exposure to Ultraviolet B (UVB) rays on the skin causesmany problems, including pigmentation and aging effect. Hence, protection against it is needed. Purpose: The study aimedto determine effect of corncob extract cream number melanin pigments in guinea pig skins exposed UVB rays. Methods: Anexperimental post-test-only control group was conducted 25 pigs. pigs were divided randomly into five groups: I without cream, II base, III hydroquinone IV 30% V 40% cream. given daily for 20 minutes before exposure 4 hours after exposure. total dose 780 mJ / cm2 28 days. amount pigment calculated using CX21 image J. Result: groups I, II, III, IV, 22.8±0.4 cells, 18±0.3 6.3±3.1 13.8±0.2 9.4±0.5 respectively. Asignificantlydifferent value One way ANOVA test <0.05. Thus, there a difference between groups. LSD post-hoc showed differences each (p <0.05). Conclusion: corn cobs effectively decreased